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What to take with collagen: vitamin C, biotin and what the trials used

You can answer this one from the record, which gives you the nutrients that sat beside collagen in published study products, the one vitamin whose authorised claim names collagen, and the list on Core's own label.

Two laughing women toasting with a small glass of collagen drink and half an orange
Image slotA woman in a cream linen shirt holding a small glass of berry-red drink beside a halved orange on a kitchen counterassets/img/blog/ww-hero.webp
In short

Vitamin C is the nutrient in Core™ whose authorised claim mentions collagen by name, and it was part of several study products set out below.

  • The claim, word for word: Vitamin C contributes to normal collagen formation for the normal function of skin.
  • What study products held: vitamin C, biotin, zinc, vitamin E, vitamin A, coenzyme Q10 or ornithine, depending on the study.
  • What Core™ holds: marine collagen with vitamin C, biotin, hyaluronic acid and six more nutrients in each portion.
Tested on our collagen
99%

of 106 women found our liquid marine collagen easy to include in their daily routine during an 8-week trial.

  • 95%felt the appearance of their skin improved
  • 89%reported more moisture and glow
  • 86%reported healthier hair

What should you take with collagen?

Vitamin C is the nutrient that appears in all three written records on this question, and Core's label adds biotin and hyaluronic acid beside it. Each record says something different.

  • The study record. Several published collagen trials tested a finished product, with collagen plus a short list of other nutrients. The next section sets out four of them.
  • The claims record. The EU keeps a list of health claims a food may carry. Vitamin C has an entry there that names collagen.1
  • The label. A Core™ portion carries vitamin C, biotin and hyaluronic acid next to its collagen, so those three are in the glass before you add anything.2

Vitamin C appears in all three records. Biotin and hyaluronic acid are the two names people ask about next.

What did the collagen trials pair it with?

In four placebo-controlled trials the collagen came with other nutrients: vitamin C, acerola extract, zinc, vitamin E, biotin, coenzyme Q10, vitamin A or ornithine, depending on the study. Each result below belongs to that study's whole product, since every participant in the collagen group took all of its ingredients at once.

Four study products and what was in them

The collagen, the nutrients beside it, and the reading each study reported.

StudyWhat the product containedWhat was measured
12-week randomised, double-blind trial in adults aged 40 to 60, about 90% of them women (48 on collagen, 52 on placebo)3A daily marine collagen drink: 8 g of hydrolysed collagen plus vitamin CThe expert-graded score for healthy hair appearance improved by 31.9% on average with collagen, against 9.4% with placebo. That is a change in a score. In the collagen group, the authors reported skin hydration +13.8% and elasticity +22.7% at 12 weeks.
12-week randomised trial of 72 women aged 35 and over, 36 per group4A drink with 2.5 g of bovine collagen peptides plus acerola extract, vitamin C, zinc, vitamin E and biotinChanges from baseline in the collagen group: skin hydration +28.0% (placebo +9.0%), wrinkle depth −26.8% (placebo −6.4%), skin density +24.8% (placebo +6.8%).
12-week randomised, double-blind trial in 34 healthy women aged 40 to 65510 mL of a liquid syrup a day: 4 g of hydrolysed fish collagen plus coenzyme Q10, vitamin C, vitamin A and biotinDermis density increased and the wrinkle area around the eyes decreased versus placebo.
8-week randomised, double-blind pilot trial in 22 healthy Japanese adults aged 31 to 486A daily 30 ml drink: 10 g of fish-derived collagen peptide plus 400 mg of ornithineTransepidermal water loss was lower than placebo at 8 weeks.
All four trials were placebo-controlled. Zinc, vitamin E, vitamin A, coenzyme Q10 and ornithine appear here as contents of a study product only. They are not in Core™.

Look down the middle column and vitamin C is named again and again, with biotin beside it in the second and third products. The table does not split a result between ingredients, because a product was tested and the product is what the figures describe.

Why is vitamin C the one people name?

Vitamin C is the one people name because its link with collagen is written into food law. The EU list of permitted health claims authorises this sentence: Vitamin C contributes to normal collagen formation for the normal function of skin.1 Parallel claims exist for bones, cartilage, gums, teeth and blood vessels. Of the nutrients in Core™, it is the only one whose claim uses the word collagen.

That wording rests on a scientific opinion in which EFSA's expert panel concluded that a cause and effect relationship has been established between the dietary intake of vitamin C and normal collagen formation, with the general population as the target population.7 The claim is about vitamin C and your body's own collagen. It says nothing about collagen peptides, which is why this page keeps the two apart.

Vitamin C has to arrive from outside. Humans, unlike most animals, cannot make it in the body, so it has to come from the diet, and it is required for the biosynthesis of collagen.8 Inside that process it acts as a coenzyme for the enzymes that add hydroxyl groups to proline and lysine, a step that stabilises collagen's triple-helix structure.7

As for amounts, the adult daily reference intake for vitamin C used on EU labels is 80 mg.9 One Core™ portion has 120 mg, which is 150% of that labelling reference.2 For the chemistry in more depth, see our page on how vitamin C and collagen relate.

What about biotin and hyaluronic acid?

Biotin has two authorised claims, for hair and skin, and Core™ has 5,000 µg per portion, while hyaluronic acid has no authorised claim, so what can be said about it comes from studies. The evidence we hold for each is of a different kind, so they get separate answers.

Biotin

Biotin is a water-soluble B vitamin, also called vitamin B7, and an essential nutrient.10 Two of its authorised claims concern hair and skin. Biotin contributes to the maintenance of normal hair. Biotin contributes to the maintenance of normal skin.1 Core™ has 5,000 µg of biotin per portion.2 Our biotin page covers the vitamin on its own.

Hyaluronic acid

Hyaluronic acid has no authorised claim, so what can be said about it comes from studies, each at its own dose. A 2014 review of hyaluronic acid taken by mouth gathered randomised, double-blind, placebo-controlled studies that used 120 mg or 240 mg a day for 2 to 6 weeks in people with dry skin. The authors reported improved skin moisture versus placebo.11

A later 12-week trial of 40 adults aged 35 to 64, also randomised, double-blind and placebo-controlled, gave 120 mg a day. At 12 weeks the hyaluronic acid group had higher water content in the outer layer of facial skin and lower facial transepidermal water loss than placebo.12

Core™ carries 50 mg of hyaluronic acid per portion.2 The studies above describe 120 mg and 240 mg a day, so read them as findings for those amounts. A side-by-side of the two ingredients is in collagen vs hyaluronic acid.

What is already in one Core™ portion?

Vitamin C and biotin are both on Core's label, in the same as 11,000 mg of hydrolysed marine collagen, types I and III.2

One portion of Core™

Amounts per portion, with the share of the EU labelling reference (NRV) where the label states one.

In the portionAmountShare of NRV
Hydrolysed marine collagen, types I and III11,000 mg
Vitamin C120 mg150%
Biotin5,000 µg
Hyaluronic acid50 mg
Silica50 mg
Vitamin D60 µg
Vitamin B55 mg83%
Vitamin B61.7 mg121%
Vitamin B1224 µg960%
Selenium27.5 µg50%
Core™ product specification.2 The portion is sugar free and fat free, with 9.9 g of protein.

Collagen, vitamin C and biotin come in one pour. The remaining nutrients each have their own authorised wording, set out in what the vitamins in a collagen portion are for.

What can you mix a collagen portion into?

You can drink a collagen portion straight or stir it into water or a smoothie, the three options in Core's directions, and all of them start the same way: shake the pack and pour into the cap.2

  • Straight. Drink it from the cap. The flavour is natural berry.
  • In water. Stir the portion into a glass of water for a longer drink.
  • In a smoothie. Stir the portion into a smoothie.

One portion a day is the amount, and the pack lives in the fridge once opened.

A woman's hands tipping a cap of berry-red liquid collagen into a tall glass of water, the colour swirling
Image slotA woman's hands tipping a small measure of berry-red liquid into a tall glass of waterassets/img/blog/ww-mix.webp

What did women in our trial report?

In our user trial, 106 women took our liquid marine collagen every day for 8 weeks, and ease came out on top, as 99% found it easy to include in their daily routine.2 Their answers are about the whole drink.

99%

found it easy to include in their daily routine.

95%

felt the appearance of their skin improved.

76%

reported stronger nails.

The skin under a woman's eye and on her cheek, before and after
89%reported more moisture and glow.
A woman's hairline, before and after
86%reported healthier hair.

Participants in the 8-week user trial of our liquid marine collagen. This is what it looked like for these women in our study.

Buyers and writers have described it in their own words.

“The taste is amazing and it is sugar free! Love what it does to my hair, nails and skin.”

★★★★★

Suzanne H.Verified purchase · Amazon, United Kingdom · 26 August 2024

“I can really see the visible changes in my skin and nails.”

★★★★★

Check4YouVerified purchase · Amazon, Germany · 27 December 2023

“To my surprise, these worked.”

After around six months on 10,000 mg of marine collagen a day she reported glowier, more even skin that held on to hydration for longer, and nails that were less brittle.

Charlotte BitmeadWriting in Stylist13

Two verified buyer reviews of our liquid marine collagen as sold under our manufacturer's own label, and an independent first-person account of marine collagen published by the outlet named.

Ready to keep it to one pour a day? See what is in Core™.

Questions about what to take with collagen

Should I take vitamin C with collagen?

Core™ already pairs the two, with 120 mg of vitamin C in each portion next to the collagen. Of the nutrients in Core™, vitamin C is the one with an authorised claim that names collagen: Vitamin C contributes to normal collagen formation for the normal function of skin.

What vitamins are in Core™ besides collagen?

Each portion has vitamin C, biotin, vitamin D and vitamins B5, B6 and B12. It also has selenium, silica and 50 mg of hyaluronic acid. The full amounts are in the table above.

What did collagen studies combine collagen with?

Collagen studies combined it with vitamin C, acerola extract, zinc, vitamin E, biotin, coenzyme Q10, vitamin A or ornithine, varying by study. One marine collagen drink added vitamin C. One bovine collagen drink added acerola extract, vitamin C, zinc, vitamin E and biotin. A fish collagen syrup added coenzyme Q10, vitamin C, vitamin A and biotin, and a fish collagen drink added ornithine.

Is there biotin in a collagen portion?

Core™ has biotin, 5,000 µg per portion. Biotin contributes to the maintenance of normal hair. Biotin contributes to the maintenance of normal skin.

Does Core™ have hyaluronic acid as well as collagen?

Yes, Core™ has 50 mg of hyaluronic acid per portion. The hyaluronic acid studies cited on this page used 120 mg or 240 mg a day, so their findings are for those amounts.

Can I mix liquid collagen into a smoothie?

Yes, the directions for Core™ are to shake the pack, pour one portion into the cap, then drink it straight or stir it into water or a smoothie.

Lab tested

Made in Sweden. Tested on real skin

Core™ is made in Sweden and lab tested, and Core’s collagen peptides have been studied on women, not just described on a label.

Shop Core™
  • Clinically studied for 8 weeks. Skin-imaging analysis showed a visible reduction in eye wrinkles, forehead wrinkles and spots.
  • Trialled by 106 women. 95% said their skin looked better and 87% saw fewer fine lines and wrinkles after 8 weeks.
  • Made in Sweden to GMP, HACCP and ISO 22000 standards.
  • Low molecular weight. Hydrolysed type I and III marine collagen peptides of about 1,500 daltons.
  • The dose is on the front. 11,000 mg of marine collagen in every serving, sugar free.
A hand holding a pack of Jadenmoor Core liquid marine collagen
Why Core™

Strong results. Backed by science

Core™ is one daily serum with marine collagen and the vitamins and minerals for your skin, hair, energy, thyroid and hormones. Made in Sweden, lab tested.

Learn more

Sources

  1. Commission Regulation (EU) No 432/2012: list of permitted health claims made on foods. eur-lex.europa.eu
  2. Studies of our liquid marine collagen formula: an 8-week user trial of 106 women and an 8-week clinical study of 10 women with skin-imaging analysis, commissioned by our manufacturer, plus the product specification. Data on file with Jadenmoor.
  3. Reilly DM, Kynaston L, Naseem S, Proudman E, Laceby D. A clinical trial shows improvement in skin collagen, hydration, elasticity, wrinkles, scalp, and hair condition following 12-week oral intake of a supplement containing hydrolysed collagen. Dermatology Research and Practice, 2024;2024:8752787. pmc.ncbi.nlm.nih.gov
  4. Bolke L, Schlippe G, Gerß J, Voss W. A collagen supplement improves skin hydration, elasticity, roughness, and density: results of a randomized, placebo-controlled, blind study. Nutrients, 2019;11(10):2494. mdpi.com
  5. Žmitek K, Žmitek J, Rogl Butina M, Pogačnik T. Effects of a Combination of Water-Soluble Coenzyme Q10 and Collagen on Skin Parameters and Condition: Results of a Randomised, Placebo-Controlled, Double-Blind Study. Nutrients, 2020;12(3):618. mdpi.com
  6. Ito N, Seki S, Ueda F. Effects of Composite Supplement Containing Collagen Peptide and Ornithine on Skin Conditions and Plasma IGF-1 Levels: A Randomized, Double-Blind, Placebo-Controlled Trial. Marine Drugs, 2018;16(12):482. mdpi.com
  7. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the substantiation of health claims related to vitamin C [...] collagen formation (ID 130, 131, 136, 137, 149) [...]. EFSA Journal, 2009;7(9):1226. doi.org/10.2903/j.efsa.2009.1226
  8. National Institutes of Health, Office of Dietary Supplements. Vitamin C: Fact Sheet for Health Professionals. Updated 31 July 2025. ods.od.nih.gov
  9. Regulation (EU) No 1169/2011 on the provision of food information to consumers, Annex XIII: daily reference intakes for vitamins and minerals. eur-lex.europa.eu
  10. National Institutes of Health, Office of Dietary Supplements. Biotin: Fact Sheet for Health Professionals. Updated 10 January 2022. ods.od.nih.gov
  11. Kawada C, Yoshida T, Yoshida H, Matsuoka R, Sakamoto W, Odanaka W, Sato T, Yamasaki T, Kanemitsu T, Masuda Y, Urushibata O. Ingested hyaluronan moisturizes dry skin. Nutrition Journal, 2014;13:70. ebi.ac.uk
  12. Hsu T-F, Su Z-R, Hsieh Y-H, Wang M-F, Oe M, Matsuoka R, Masuda Y. Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study. Nutrients, 2021;13(7):2220. mdpi.com
  13. Bitmead C. I didn't believe collagen supplements were effective until I tried this. Stylist. stylist.co.uk