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What age should you start taking collagen? The ages the trials enrolled

Nobody can hand you a birthday for this. You can check when skin's own collagen begins to change and how old the people were in the collagen studies. Both are set out below, with every study's age range in one table.

Three women of different ages leaning together and laughing, one holding a small glass of liquid collagen
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In short

The studies give enrolled ages, not a starting age. The collagen trials on this page took in adults from their twenties and thirties to their seventies, and skin's own collagen output begins to ease from early adulthood.

  • Widest range: 20 to 70. Those were the ages of the 1,125 participants in a pooled analysis of 19 randomised double-blind trials.
  • Youngest single trial: from 30. It enrolled 71 healthy women aged 30 to 60 and tested fish-scale collagen peptides for 12 weeks.
  • Oldest: up to 75. A 16-week hair trial of collagen peptides enrolled 44 healthy women aged 39 to 75.
Tested on our collagen
95%

of 106 women felt the appearance of their skin improved after 8 weeks on our liquid marine collagen.

  • 99%found it easy to include in their daily routine
  • 87%noticed fewer fine lines and wrinkles
  • 81%reported firmer skin

What age should you start taking collagen?

No study names one starting age for collagen, and the published studies enrolled adults aged 20 to 75 between them, so the figure you can check is the age range each one wrote into its enrolment.

The widest comes from a meta-analysis of 19 randomised double-blind trials, which counted 1,125 participants aged 20 to 70, about 95% of them women.1 Among the single trials collected here, the lowest entry age was 30, in a study of 71 healthy women aged 30 to 60.2 The highest upper limit was 75, in a hair trial of 44 healthy women aged 39 to 75.3

The answer is a span, and you can look for your own age inside it.

When does skin's own collagen start to change?

Skin's own collagen starts to change in early adulthood, when the skin begins making about 1.0% to 1.5% less collagen each year.4 The figure is a yearly rate with no birthday attached, which is one reason the question of age has no neat reply.

A separate paper looks at a later stage and reports that as much as 30% of skin collagen is lost in the first five years after menopause.5 Total skin collagen then declines by an average of 2.1% per postmenopausal year over 15 years.5

Two women laughing on a terrace bench, one passing the other a small glass of berry-red collagen drink
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What ages did the collagen trials enrol?

The collagen studies on this page enrolled participants aged 20 to 75 between them, and the table below sorts every one by the youngest age it accepted. Find the rows that include your age, then read across to see what was taken and what was measured.

Collagen studies sorted by the youngest age enrolled

One row per study: the ages, the people and the daily amount, and what that study recorded.

Ages enrolledWho took part and what they tookWhat the study measured
20 to 701,125 participants, about 95% women, across 19 randomised double-blind trials of hydrolysed collagen pooled in a meta-analysis.1The authors concluded that 90 days of hydrolysed collagen reduced wrinkles and improved skin elasticity and hydration.
30 to 6071 healthy women. 20 ml a day containing 3,000 mg of fish-scale collagen peptides, or placebo, for 12 weeks.2Periorbital wrinkles fell significantly versus placebo. Facial skin moisture and elasticity rose in the collagen group.
31 to 4822 healthy Japanese adults in a pilot trial. A daily 30 ml drink with 10 g of fish-derived collagen peptide plus 400 mg ornithine, for 8 weeks.6Lower transepidermal water loss than placebo at 8 weeks.
35 to 5099 healthy Japanese women. 1 g or 5 g of collagen peptides daily for 12 weeks.7Water content in the stratum corneum and epidermis increased, transepidermal water loss was lower and natural moisturising factor in the stratum corneum was higher.
35 to 5569 women. 2.5 g or 5.0 g of collagen hydrolysate, or placebo, once daily for 8 weeks.8Skin elasticity improved significantly in both collagen groups compared with placebo.
35 to 60Adults with dry skin, 50 randomised and 44 completed. 1,000 mg a day of fish-scale collagen peptides for 12 weeks.9A skin moisture reading on the forearm improved by 7.33% versus 2.83% with placebo, and natural moisturising factor in the stratum corneum ended higher than with placebo.
35 and over72 women. A drink with 2.5 g of bovine collagen peptides plus acerola extract, vitamin C, zinc, vitamin E and biotin, or placebo, for 12 weeks.10From baseline in the collagen group: skin hydration +28.0% (placebo +9.0%) and wrinkle depth −26.8% (placebo −6.4%).
39 to 7544 healthy women. 2.5 g of collagen peptides a day, or placebo, for 16 weeks.3Hair thickness rose by 1.93 micrometres on average with collagen, against a slight dip of 0.99 micrometres with placebo. The difference between groups was significant.
40 to 6064 women. 1,000 mg a day of low-molecular-weight fish collagen peptide, or placebo, for 12 weeks.11Skin hydration significantly higher than placebo at 6 weeks and at 12 weeks. Crow's-feet wrinkling and skin elasticity significantly better than placebo at 12 weeks.
40 to 60Adults, about 90% of them women. A daily marine collagen drink with 8 g of hydrolysed collagen plus vitamin C, or placebo, for 12 weeks.12In the collagen group at 12 weeks, the authors reported hydration +13.8% and elasticity +22.7%.
45 to 60Women. 10 g a day of hydrolysed fish collagen, or placebo, for 12 weeks.13Wrinkle score fell 35% from baseline on the right side of the face, a 24% greater reduction than placebo.
45 to 60Menopausal women. 5 g a day of collagen from freshwater fish skin, or placebo, for 6 months.14Skin elasticity improved by 12.23% from baseline in the collagen group of 20 women, significantly more than placebo.
45 to 65114 women. 2.5 g of collagen peptides a day, or placebo, for 8 weeks.15Eye-wrinkle volume significantly lower than placebo after 4 weeks and after 8 weeks (about 20%).
Each row is one published study with its own participants, ingredient, amount and measurement. The rows are sorted by age so you can find yourself in them. The table does not rank one age against another.

Lined up like this, the ranges overlap heavily, so you may find your age in several rows at once. The ingredients and the measurements differ from row to row, so each result belongs to the product in its own row. If you want the studies grouped by decade instead, we have done that in collagen after 40 and collagen after 50.

Is your thirties too early? Is your sixties too late?

Both decades sit inside the age ranges the studies enrolled, with several opening at 30, 31 or 35 and the oldest ranges reaching 65, 70 and 75.

If you are in your thirties

Several studies on this page opened their doors at 30, 31 or 35, so you have company in the data.

  • From 30. The 12-week trial of fish-scale collagen peptides took healthy women aged 30 to 60.2
  • From 31. The 8-week pilot of a fish-derived collagen peptide drink with ornithine recruited healthy Japanese adults aged 31 to 48.6
  • From 35. One trial enrolled healthy Japanese women aged 35 to 50,7 another women aged 35 to 55,8 a third adults aged 35 to 60 with dry skin,9 and a fourth women aged 35 and over.10

For your twenties, this page has one entry, the pooled analysis, whose participants were aged 20 to 70.1

If you are in your sixties

Several studies enrolled people in their sixties, though many of the age ranges in the table close at 60. The eye-wrinkle trial of 114 women went to 65.15 The pooled analysis reached 70,1 and the hair trial of 44 healthy women reached 75.3 One study enrolled women aged 35 and over.10

In your thirties or in your sixties, there are studies here whose age range includes yours.

What is in one Core™ portion?

Core™ puts 11,000 mg of hydrolysed marine collagen, types I and III, into a single portion. Across the clinical trials behind this article, the daily amount ran between 1 g and 10 g of collagen peptides. It has a natural berry flavour and is sugar free and fat free.16

Alongside the collagen come nutrients whose roles are authorised health claims in the EU:17

  • Vitamin C. Each portion has 120 mg, and vitamin C contributes to normal collagen formation for the normal function of skin.
  • Biotin. Each portion has 5,000 µg, and biotin contributes to the maintenance of normal skin.
  • Selenium. Each portion has 27.5 µg, and selenium contributes to the maintenance of normal nails.
  • Vitamin D. Each portion has 60 µg, and vitamin D contributes to the maintenance of normal bones.

Hyaluronic acid and silica are in there as well, at 50 mg each.16 You take one portion a day. Shake, pour it into the cap, then drink it as it is or stirred into water or a smoothie. The Core™ product page has the full label.

What did women report on our liquid marine collagen?

In our user trial of our liquid marine collagen, 95% of women felt the appearance of their skin improved, 89% reported more moisture and glow and 99% found it easy to include in their daily routine. The 106 women took it every day for 8 weeks and then answered questions about what they had noticed, whereas the table above is other people's research on other formulas.16

95%

felt that the appearance of their skin improved.

89%

reported more moisture and glow.

99%

found it easy to include in their daily routine.

Those figures are shares of the 106 women, drawn from their own answers. In that trial, women reported visible results in as little as 4 weeks, with further improvement by week 8.16 The week-by-week view is in our guide to how long collagen takes to work.

Two women, two starting points

Studies speak for groups, while the two accounts below are from one woman each, and both happen to mention her age.

“My skin looks great, with no fine lines. I'm 45 and will definitely keep using it.”

★★★★★

FrédériqueVerified purchase · Amazon, France · 18 May 2024

“My nails were the best I had ever had in my whole life.”

Her own starting line was her birthday: she took up marine collagen after turning 40. She wrote that her skin was more hydrated within the first month, and that by month six her hair felt thicker and fuller.

Charlotte DormonWriting in Hip & Healthy18

A verified buyer review of our liquid marine collagen as sold under our manufacturer's own label, and an independent first-person account of marine collagen published by the outlet named.

Questions about collagen and age

What age should I start taking collagen?

No study sets a starting age for collagen; the studies on this page record enrolled ages instead. A pooled analysis of 19 trials covered participants aged 20 to 70, and the single trials here ran from a lower limit of 30 to an upper limit of 75.

Is 30 too early for collagen?

Thirty is inside the studied age range, as one trial on this page enrolled healthy women from 30: 71 of them, aged 30 to 60, drank 20 ml a day containing 3,000 mg of fish-scale collagen peptides or placebo for 12 weeks. The pooled analysis on this page covered participants aged 20 to 70.

Is it too late to start collagen in your sixties?

Your sixties are within the studied ages, as several age ranges on this page reach past 60. A trial of 114 women took ages 45 to 65, a hair trial of 44 healthy women took ages 39 to 75, and the pooled analysis covered participants aged 20 to 70.

When does collagen in skin start to decline?

Collagen in skin starts to decline from early adulthood, according to a review of skin collagen through the life stages: the skin makes about 1.0% to 1.5% less collagen each year. A separate paper reports that as much as 30% of skin collagen is lost in the first five years after menopause.

How much collagen did the studies use?

Daily amounts in the clinical trials behind this article ran between 1 g and 10 g of collagen peptides, and each row of the table gives its own. Core™ has 11,000 mg of hydrolysed marine collagen per portion.

Lab tested

Made in Sweden. Tested on real skin

Core™ is made in Sweden and lab tested, and Core’s collagen peptides have been studied on women, not just described on a label.

Shop Core™
  • Clinically studied for 8 weeks. Skin-imaging analysis showed a visible reduction in eye wrinkles, forehead wrinkles and spots.
  • Trialled by 106 women. 95% said their skin looked better and 87% saw fewer fine lines and wrinkles after 8 weeks.
  • Made in Sweden to GMP, HACCP and ISO 22000 standards.
  • Low molecular weight. Hydrolysed type I and III marine collagen peptides of about 1,500 daltons.
  • The dose is on the front. 11,000 mg of marine collagen in every serving, sugar free.
A hand holding a pack of Jadenmoor Core liquid marine collagen
Why Core™

Strong results. Backed by science

Core™ is one daily serum with marine collagen and the vitamins and minerals for your skin, hair, energy, thyroid and hormones. Made in Sweden, lab tested.

Learn more

Sources

  1. de Miranda RB, Weimer P, Rossi RC. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. International Journal of Dermatology, 2021;60(12):1449–1461. doi.org/10.1111/ijd.15518
  2. Koizumi S, Inoue N, Shimizu M, et al. Effects of Dietary Supplementation with Fish Scales-Derived Collagen Peptides on Skin Parameters and Condition: A Randomized, Placebo-Controlled, Double-Blind Study. International Journal of Peptide Research and Therapeutics, 2018;24(3):397-402. link.springer.com
  3. Oesser S. The oral intake of specific bioactive collagen peptides has a positive effect on hair thickness. Nutrafoods, 2020;1:134–138. nutrafoods.eu
  4. Reilly DM, Lozano J. Skin collagen through the lifestages: importance for skin health and beauty. Plastic and Aesthetic Research, 2021;8:2. oaepublish.com
  5. Calleja-Agius J, Muscat-Baron Y, Brincat MP. Skin ageing. Menopause International, 2007;13(2):60–64. um.edu.mt
  6. Ito N, Seki S, Ueda F. Effects of Composite Supplement Containing Collagen Peptide and Ornithine on Skin Conditions and Plasma IGF-1 Levels: A Randomized, Double-Blind, Placebo-Controlled Trial. Marine Drugs, 2018;16(12):482. mdpi.com
  7. Miyanaga M, Uchiyama T, Motoyama A, Ochiai N, Ueda O, Ogo M. Oral Supplementation of Collagen Peptides Improves Skin Hydration by Increasing the Natural Moisturizing Factor Content in the Stratum Corneum: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Skin Pharmacology and Physiology, 2021;34(3):115-127. karger.com
  8. Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacology and Physiology, 2014;27(1):47-55. karger.com
  9. Jung K, Kim S-H, Joo K-M, Lim S-H, Shin J-H, Roh J, Kim E, Park CW, Kim W. Oral Intake of Enzymatically Decomposed AP Collagen Peptides Improves Skin Moisture and Ceramide and Natural Moisturizing Factor Contents in the Stratum Corneum. Nutrients, 2021;13(12):4372. mdpi.com
  10. Bolke L, Schlippe G, Gerß J, Voss W. A collagen supplement improves skin hydration, elasticity, roughness, and density: results of a randomized, placebo-controlled, blind study. Nutrients, 2019;11(10):2494. mdpi.com
  11. Kim DU, Chung HC, Choi J, Sakai Y, Lee BY. Oral intake of low-molecular-weight collagen peptide improves hydration, elasticity, and wrinkling in human skin: a randomized, double-blind, placebo-controlled study. Nutrients, 2018;10(7):826. mdpi.com
  12. Reilly DM, Kynaston L, Naseem S, Proudman E, Laceby D. A clinical trial shows improvement in skin collagen, hydration, elasticity, wrinkles, scalp, and hair condition following 12-week oral intake of a supplement containing hydrolysed collagen. Dermatology Research and Practice, 2024;2024:8752787. pmc.ncbi.nlm.nih.gov
  13. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. Journal of Cosmetic Dermatology, 2021;20(3):825–834. pmc.ncbi.nlm.nih.gov
  14. Duangjai A, Srivilai J, Nangola S, Amornlerdpison D. Calcium and vitamin D supplementation with and without collagen on bone density and skin elasticity in menopausal women: a randomized controlled study. Clinics and Practice, 2025;15(9):168. pmc.ncbi.nlm.nih.gov
  15. Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacology and Physiology, 2014;27(3):113–119. doi.org/10.1159/000355523
  16. Studies of our liquid marine collagen formula: an 8-week user trial of 106 women and an 8-week clinical study of 10 women with skin-imaging analysis, commissioned by our manufacturer, plus the product specification. Data on file with Jadenmoor.
  17. Commission Regulation (EU) No 432/2012: list of permitted health claims made on foods. eur-lex.europa.eu
  18. Dormon C. I took collagen for 6 months and this is what happened. Hip & Healthy, 4 November 2020. hipandhealthy.com